Dr. Seema Prakash and Dr. Jitendra Prakash established In Vitro International Private Limited in 1995 in Bangalore, India. 

IVI was established with the aim of translating the Glass Bead Liquid Culture Technology invention on a large scale and promoting the vision of taking the benefits of biotechnology to the economically and socially weaker sections of global population. 

Today, IVI is responsible for nearly 50% of the country's tissue culture export market.

Dr. Seema Prakash received her Master of Science Degree in Botany, with specialization in Genetics and Plant Breeding, and received advanced training in tissue culture research in England. She was awarded the Ph.D. degree from Bangalore University for her work on ''Cost-Effective Micropropagation''. 

Dr. Seema Prakash's discovery of Glass Bead Liquid Culture Media Technology brings down the cost of media by 94% on per plant basis and has far reaching implications on commercial tissue culture and horticulture. Further refinement of this technology may even replace the need for automation of micropropagation in the developed world, and result in the application of plant tissue culture at grassroots level in the developing countries. 

At the Asia Pacific Convention for Entrepreneurial Women held in April 2002, Dr. Seema Prakash was awarded the prestigious AWAKE Award in the Biotechnology Sector for her entrepreneurial spirit and initiative. She was also awarded the ''Rajiv Gandhi Shiromani Award'', the ''Industrial Excellence Award'' and the ''Deluxe Green Label Woman Achievers Award'' in 2002. Dr. Seema Prakash was conferred the ''Pride of India'' Award in 2003.  

Dr. Jitendra Prakash has more than 25 years experience in commercial tissue culture and seed industry and was personally responsible for setting up 6 large tissue culture laboratories worldwide. To date more than 500 million tissue culture plants have been produced under his direct supervision.
Dr. Prakash was the first to develop a production system for disease-free seed potato on a commercial scale using tissue culture and demonstrate the expression of single gene (potato virus X) resistance at the cellular level which formed the basis of ''Genetic Engineering for Disease Resistance'' worldwide.

After obtaining specialized work experience as a Virologist and Biotechnologist at University College, Dublin, Dr. Prakash worked for several years Cell Biologist, Group Leader- Germplasm Development Group: Head - Plant Health Services Division, and Deputy Director of Research, Twyford Plant Laboratories, Somerset, and Programme Co-ordinator- Twyford Centre for Advanced  Technologies, Cambridge, England. As Group Leader-Germplasm Development, Dr. Prakash also headed the Research and Development wing of Asmeer Seeds (a subsidiary of Twyford Plant Laboratories), and evolved several new strains of tomato, cauliflower and cabbage. He has contributed in breeding new varieties of potato, lilies and rapeseed oil.  His work on commercial tissue culture, genetic engineering and plant breeding came into limelight when he invited His Royal Highness, The Duke of Kent to try his hand at tissue culture on 14th November, 1984. Dr. Prakash returned to India in 1987 and was instrumental in setting up India's first commercial tissue culture laboratory. Dr. Prakash was awarded the title of ''Eurobiologist''.   

Dr. Prakash's research activities and achievements have been covered worldwide by the both electronic and print media innumerable times and he has been rated by leading business magazines as one of the ten foremost commercial biotechnologists in the world.